The OPERAM study has started recently and over 100 patients are included in the participating centra (Bern, Louvain, Utrecht). The expectation is that in Cork inclusion will start soon as well. In this study the effect of a systematic medication review will be investigated in old patients admitted to a hospital. The goal is to improve avoidable hospital admission by reducing adverse effects and inappropriate medication. The study uses the STRIPassistant, a computerized support system for the Systematic Tool to Reduce Inappropriate Prescribing (STRIP). The results of the study are expected in 2020.